Oregon grape is used for liver toxicity from drugs or alcohol; low stomach acid (poor protein assimilation); infections; or irritation in the intestines (irritable bowel syndrome). It cools the liver, stimulates bile flow, reduces intestinal inflammation, and benefits symptoms of dermatitis. It is one of the most effective herbs for skin disorders such as acne, psoriasis, or cysts, for which it can be used with burdock seed. Oregon grape root has been recommended for heat in the stomach with such symptoms as tooth and gum pain, inflamed gums, a burning and gnawing feeling in the stomach area, styes, and facial acne. It may also be useful for vaginal yeast infections, especially when the discharge is slightly yellow and strongly smelling.